Silencing of SARS-CoV spike gene by small interfering RNA in HEK 293T cells
نویسندگان
چکیده
منابع مشابه
Small interfering RNA-induced transcriptional gene silencing in human cells.
Small interfering RNA (siRNA) and microRNA silence genes at the transcriptional, posttranscriptional, and/or translational level. Using human tissue culture cells, we show that promoter-directed siRNA inhibits transcription of an integrated, proviral, elongation factor 1alpha (EF1A) promoter-green fluorescent protein reporter gene and of endogenous EF1A. Silencing was associated with DNA methyl...
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ژورنال
عنوان ژورنال: Biochemical and Biophysical Research Communications
سال: 2004
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2004.09.180